Inhibition of Protein N-Glycosylation Blocks SARS-CoV-2 Infection
ABSTRACT Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) extensively N-glycosylates its spike proteins, which are necessary for host cell invasion and the target of both vaccines and immunotherapies.These N-glycans are predicted to modulate spike binding to the host receptor by stabilizing its open conformation and host immunity evasio